DC Chemicals — Chemicals for Life Science
← DC67456 product
PRODUCT DATASHEET · DC67456

Lipid U 105

Version 1.969282f1 · 2026-09-13

Download full product guide
CAS No.Not available
Chemical NameLipid U 105
Synonymsdi(heptadecan-9-yl) 6,6'-((3-(bis(2-hydroxyethyl)amino)propyl)azanediyl)dihexanoate,Lipid-U-105, U105
SMILESCCCCCCCCC(CCCCCCCC)OC(CCCCCN(CCCCCC(OC(CCCCCCCC)CCCCCCCC)=O)CCCN(CCO)CCO)=O
FormulaC53H106N2O6
M.Wt867.4
Purity>98%
StorageOriginal product: up to 1 year under the storage conditions stated on the vial, kept tightly sealed. Stock solutions: aliquots at -20°C, generally up to one month.
Shipping conditionShips from Shanghai. Pure lipid is stable during ice-pack transport.
PublicationNot available

Lipid U 105 is an ionizable cationic lipid (pKa 6.65) specifically designed for circular RNA delivery via LNPs. These formulations effectively enhance VEGF-A expression in HUVECs, promoting endothelial cell proliferation and migration. When applied topically in diabetic mouse models, the VEGF-A-encoding circular RNA LNPs significantly accelerate wound healing, demonstrating therapeutic potential for impaired tissue repair.

Specifications shown are product-page values, not batch test results.

Read Instructions for Use →