DC Chemicals

DC67292 · Updated 28 October 2026

IAJD34

Instructions for Use

Before use

Check the supplied lot number, batch COA, approved SDS, quantity and retest date. Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light.

For small quantities of viscous or oily lipid, volumetric transfer can reduce weighing losses. Confirm solvent compatibility and solubility before preparing a stock; calculated volumes do not establish solubility.

Stock-solution planning

Volume (mL) = mass (mg) × 1000 / [molecular weight × concentration (mM)].

Mass10 mM20 mM
10 mg0.7179 mL0.3590 mL
25 mg1.7948 mL0.8974 mL
50 mg3.5896 mL1.7948 mL
100 mg7.1792 mL3.5896 mL

Literature formulation reference

ComponentDC Chemicals productMolecular weightMolar ratioMass at 1 µmol total lipid (mg)
IAJD34DC672921392.911001.392910

IAJD34 is 100% of the carrier amphiphile; RNA is listed separately. The reported IAJD34:mRNA mass ratio is 40:1. Assembly used 10 mM acetate at pH 4.0. N/P was not established in this review and is not inferred from the mass ratio.

Read the complete study conditions, biological results, tolerability and figures →

References

  1. Meshanni JA et al. Targeted delivery of TGF-β mRNA to murine lung parenchyma using one-component ionizable amphiphilic Janus Dendrimers. Nature Communications 16, 1806 (2025). DOI: 10.1038/s41467-025-56448-y