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IAJD34
Formulation & Performance
Literature-reported formulation composition
| Component | mol% | Role |
|---|---|---|
| IAJD34 | 100 | Ionizable lipid |
| Reported total | 100 | Source values retained |
Component molecular weights and calculated amounts
Composition retained from the cited study below. Research planning aid only. Results cover lipid component weights and do not include RNA, buffer, solvent, process loss or an N/P ratio.
| Component | Molecular weight | Molar parts | Normalized mol% | Amount (µmol) | Weight (mg) |
|---|---|---|---|---|---|
| IAJD34 | 100.000 | 71.7921 | 100.0000 |
Calculated total: 100.0000 mg lipid.
Calculated catalog planning quantities; RNA, solvent and process loss are excluded. DMG-PEG2000 uses 2507. Component mass = total lipid mass × molar parts × molecular weight / sum(parts × molecular weight). This conversion does not infer N/P.
Literature-reported performance for the cited formulation
Literature-reportedPredominantly lung expression10 micrograms Luc mRNA/mouse; ex vivo organ imaging · 4 hMain PDF p.3, Fig.1B
Literature-reported3.12 × 10^7 ± 9.15 × 10^6 photons/s10 micrograms/mouse; whole-body signal, not lung-only flux · 4 hMain PDF p.2 and Fig.1D
Literature Data DisclaimerAll formulation parameters and performance values shown in this section are derived from the cited publication and are provided for reference only. These results were obtained using the specific materials, formulation process, cargo, dose, analytical method, model and administration route described in that study. Unless otherwise stated, the data were not generated or independently verified by DC Chemicals. DC Chemicals supplies the lipid compound only and does not guarantee that customers will reproduce the reported LNP properties or biological performance.
The administration route shown above was used in the cited study and is not a clinical-use instruction or recommendation by DC Chemicals.
The administration route shown above was used in the cited study and is not a clinical-use instruction or recommendation by DC Chemicals.
Cited literature for this formulation and performance datasetTargeted delivery of TGF-β mRNA to murine lung parenchyma using one-component ionizable amphiphilic Janus Dendrimers. DOI: 10.1038/s41467-025-56448-y DOI: 10.1038/s41467-025-56448-y
100% denotes the single lipid species only, excluding RNA and solvent. There are no helper lipids. At 30 micrograms TGF-beta mRNA the study reports inflammatory/liver-marker findings; reporter tolerability is not general therapeutic safety.
100% denotes the single lipid species only, excluding RNA and solvent. There are no helper lipids. At 30 micrograms TGF-beta mRNA the study reports inflammatory/liver-marker findings; reporter tolerability is not general therapeutic safety.