DC Chemicals

DC67292 · Updated 28 October 2026

IAJD34

Product Datasheet

IAJD34 is a one-component ionizable amphiphilic Janus dendrimer studied for lung-directed mRNA delivery in mice. Published experiments include luciferase expression, transient TGF-β production, dose-dependent tolerability and an acute lung-injury model.

CAS No.Not available
Chemical NameIAJD34
SynonymsIAJD-34, IAJD 34
SMILESCCCCCCCCCCCOC1=CC(OCCCCCCCCCCC)=CC(CNC(=O)C2=CC(OCCOCCOCCOC(=O)CCCN3CCCCC3)=C(OCCOCCOCCOCC3=CC=CC=C3)C(OCCOCCOCCOC(=O)CCCN3CCCCC3)=C2)=C1
FormulaC79H129N3O17
M.Wt1392.91
Purity>95% by ELSD-HPLC
StoragePure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light.
Shipping conditionShips from Shanghai. Pure lipid is stable during ice-pack transport.
Publication
  1. Meshanni JA et al. Targeted delivery of TGF-β mRNA to murine lung parenchyma using one-component ionizable amphiphilic Janus Dendrimers. Nature Communications 16, 1806 (2025). DOI: 10.1038/s41467-025-56448-y

Research evidence

Read detailed Formulation & Performance

Specifications are catalog specifications, not batch test results.