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YSK12-C4 (YSK12-MEND)

Version 1.d5a7e4f2 · 2026-09-13

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CAS No.Not available
Chemical NameYSK12-C4 (YSK12-MEND)
Synonyms6,9,28,31-Heptatriacontatetraen-19-ol, 19-[4-(dimethylamino)butyl]-, (6Z,9Z,28Z,31Z)-;YSK12C4， YSK12 C4
SMILESCCCCC/C=C\C/C=C\CCCCCCCCC(CCCCN(C)C)(O)CCCCCCCC/C=C\C/C=C\CCCCC
FormulaC43H81NO
M.Wt628.109353780746
PurityELSD-HPLC>95%
StorageOriginal product: up to 1 year under the storage conditions stated on the vial, kept tightly sealed. Stock solutions: aliquots at -20°C, generally up to one month.
Shipping conditionShips from Shanghai. Pure lipid is stable during ice-pack transport.
PublicationNakamura T, et al. Small-sized, stable lipid nanoparticle for the efficient delivery of siRNA to human immune cell lines. Sci Rep. 2016 Nov 28;6:37849.

YSK 12C4 is an ionizable cationic lipid primarily used to enhance siRNA cellular delivery via multifunctional envelope-type nanodevices (MEND). YSK 12C4 promotes siRNA uptake and endosomal escape, effectively silencing genes in human immune cell lines.

Specifications shown are product-page values, not batch test results.

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