DC60821 · Updated 27 October 2026
Lipid TOT-5
Instructions for Use
Before use
Check the supplied lot number, batch COA, approved SDS, quantity and retest date. Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light.
For small quantities of viscous or oily lipid, volumetric transfer can reduce weighing losses. Confirm solvent compatibility and solubility before preparing a stock; calculated volumes do not establish solubility.
Stock-solution planning
Volume (mL) = mass (mg) × 1000 / [molecular weight × concentration (mM)].
| Mass | 10 mM | 20 mM |
|---|---|---|
| 10 mg | 0.9490 mL | 0.4745 mL |
| 25 mg | 2.3726 mL | 1.1863 mL |
| 50 mg | 4.7452 mL | 2.3726 mL |
| 100 mg | 9.4904 mL | 4.7452 mL |
Literature formulation reference
| Component | DC Chemicals product | Molecular weight | Molar ratio | Mass at 1 µmol total lipid (mg) |
|---|---|---|---|---|
| TOT-5 | DC60821 | 1053.693 | 65 | 0.674779 |
| DSPC | DC57005 | 790.15 | 15 | 0.116771 |
| Cholesterol | DCD-041 | 386.65 | 20 | 0.076187 |
| DMG-PEG2000 | DC40169 | 2507 | 1.5 | 0.037049 |
The source labels 65:15:20:1.5 as mol%, although these entries sum to 101.5. Here they are reproduced as relative molar parts; calculated masses normalize by 101.5 and are not an author-reported correction. The study calls this formulation 15%DSPC. Its 3%DSPC comparator is 65:3:32:1.5. DMG-PEG2000 uses the DC Chemicals nominal average molecular weight 2507.
Read the complete study conditions, biological results, tolerability and figures →