Literature-reported formulation composition
Component: Si5-N14 | mol%: 35 | Role: Ionizable lipid
Search the tables and observations reproduced from the product literature guide. Rows may represent measurements, recipes or experimental context; they are not all independent experiments.
Component: Si5-N14 | mol%: 35 | Role: Ionizable lipid
Component: DOPE | mol%: 16 | Role: Helper phospholipid
Component: Cholesterol | mol%: 46.5 | Role: Sterol
Component: C14PEG2K (DMPE-PEG2000 as named in SI) | mol%: 2.5 | Role: PEG lipid
Component: Reported total | mol%: 100 | Role: Source values retained
Literature-reported Reported lead-organ delivery Lung-directed lead FLuc reporter screen; 0.25 mg/kg IV; expression is distinct from lipid accumulation · 6 h Main PDF p.6, Fig.3
Literature-reported Apparent LNP pKa 6.92 TNS assay; formulation-dependent Main PDF p.6; SI Fig.S28