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Si5-N14

Version 1.d528dc13 · 2026-09-13

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CAS No.Not available
Chemical NameSi5-N14
SynonymsSi5N14， Si5 N14
SMILESO=C(CCN(CCC[Si](C)(C)O[Si](C)(CCCN(CCC(NCCCCCCCCCCCCCC)=O)CCC(NCCCCCCCCCCCCCC)=O)C)CCC(NCCCCCCCCCCCCCC)=O)NCCCCCCCCCCCCCC
FormulaC78H160N6O5Si2
M.Wt1,318.3
PurityELSD-HPLC>95%
StorageOriginal product: up to 1 year under the storage conditions stated on the vial, kept tightly sealed. Stock solutions: aliquots at -20°C, generally up to one month.
Shipping conditionShips from Shanghai. Pure lipid is stable during ice-pack transport.
PublicationCombinatorial design of siloxane-incorporated lipid nanoparticles augments intracellular processing for tissue-specific mRNA therapeutic delivery-Michael J. Mitchell -Nature Nanotechnology (2024)

Si5-N14 is a lipid-based molecule engineered with siloxane groups, designed specifically for efficient mRNA delivery to the lungs. The incorporation of siloxane units boosts the cellular uptake of mRNA-loaded lipid nanoparticles (LNPs) and enhances their ability to escape from endosomes. These properties significantly increase the overall effectiveness of mRNA delivery, making Si5-N14 a promising tool for targeted therapeutic applications.

Specifications shown are product-page values, not batch test results.

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