DC60545 · Updated 28 October 2026

200Oi10

Product Datasheet

200Oi10 is an ionizable lipidoid evaluated in a comparative mouse study of pancreatic mRNA delivery. Its reported activity depends on administration route and helper-lipid composition. The paper subsequently focuses on 306Oi10; those later macrophage-transfer, beta-cell and tolerability results are not evidence for 200Oi10.

CAS No.	Not available
Chemical Name	200Oi10
Synonyms	200,Oi,10， 200Oi,10
SMILES	CC(C)CCCCCCCOC(=O)CCN(CCC(=O)OCCCCCCCC(C)C)CCN(CCC(=O)OCCCCCCCC(C)C)CCN1CCN(CCN(CCC(=O)OCCCCCCCC(C)C)CCC(=O)OCCCCCCCC(C)C)CC1
Formula	C75H145O10N5
M.Wt	1,277.01
Purity	>95% by ELSD-HPLC
Storage	Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light.
Shipping condition	Ships from Shanghai. Pure lipid is stable during ice-pack transport.
Publication	Melamed JR et al. Ionizable lipid nanoparticles deliver mRNA to pancreatic beta cells via macrophage-mediated gene transfer. Science Advances 9, eade1444 (2023). DOI: 10.1126/sciadv.ade1444. Complete supporting information: Figure S1 and Figures S3-S8; main Figures 1B and 2B define the target-specific evidence.

Research evidence

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Specifications are catalog specifications, not batch test results.