Literature-reported formulation composition
Component: 4A3-SCC-PH | Reported molar ratio: 15 | Role: Ionizable lipid
Search the tables and observations reproduced from the product literature guide. Rows may represent measurements, recipes or experimental context; they are not all independent experiments.
Component: 4A3-SCC-PH | Reported molar ratio: 15 | Role: Ionizable lipid
Component: DOPE | Reported molar ratio: 15 | Role: Helper phospholipid
Component: Cholesterol | Reported molar ratio: 30 | Role: Sterol
Component: DMG-PEG2000 | Reported molar ratio: 3 | Role: PEG lipid
Component: Reported ratio sum | Reported molar ratio: 63 | Role: Original ratio retained
Literature-reported Liver FLuc expression versus MC3 LNP 176-fold higher 0.1 mg/kg FLuc mRNA; mouse IV comparison · 6 h Main PDF pp.4-5, Fig.3
Literature-reported Cre-mediated hepatocyte reporter activation 99% 0.2 mg/kg Cre mRNA; tdTomato reporter mice; recombination readout · 2 days Main PDF pp.8-9, Fig.5; SI p.30