PRODUCT DATASHEET · DC60506
IR-117-17
Version 1.03100af8 · 2026-09-13
| CAS No. | Not available |
| Chemical Name | IR-117-17 |
| Synonyms | A10-LIN;IR11717 IR 117 17 |
| SMILES | CCCCC/C=C\C/C=C\CCCCCCCC(OCCCCCC(C(CCCCOC(CCCCCCC/C=C\C/C=C\CCCCC)=O)CNCCCN(CCCC)CCCC)O)=O |
| Formula | C59H110N2O5 |
| M.Wt | 927.52 |
| Purity | 98% |
| Storage | Original product: up to 1 year under the storage conditions stated on the vial, kept tightly sealed. Stock solutions: aliquots at -20°C, generally up to one month. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | Not available |
IR-117-17 (A10-LIN) is an ionizable and biodegradable lipid specifically designed for nebulized mRNA delivery. When formulated into lipid nanoparticles (LNPs), IR-117-17 demonstrates remarkable efficacy, achieving a 300-fold enhancement in lung mRNA delivery compared to the best-performing LNP previously reported. Additionally, it shows a two-fold improvement over the leading PBAE-based delivery system, with up to a 45-fold increase in mRNA delivery efficiency to the large airways.
Specifications shown are product-page values, not batch test results.
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