PRODUCT DATASHEET · DC60494
76-O17Se
Product Datasheet
Version 1.d7bd4b79 · 2026-09-13
| CAS No. | Not available |
| Chemical Name | 76-O17Se |
| Synonyms | 76O17Se， 76 O17Se |
| SMILES | CCCCCCCCCCCCCC[Se]CCOC(=O)CCN(CCC(=O)OCC[Se]CCCCCCCCCCCCCC)CCN1CCCC1 |
| Formula | C44H86O4N2Se2 |
| M.Wt | 865.10 |
| Purity | >95% by ELSD-HPLC |
| Storage | Original product: up to 1 year under the storage conditions stated on the vial, kept tightly sealed. Stock solutions: aliquots at -20°C, generally up to one month. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | Ye Z et al. In Vitro Engineering Chimeric Antigen Receptor Macrophages and T Cells by Lipid Nanoparticle-Mediated mRNA Delivery. ACS Biomater Sci Eng. 2022;8(2):722-733. DOI: 10.1021/acsbiomaterials.1c01532. Li Y et al. Combinatorial library of chalcogen-containing lipidoids for intracellular delivery of genome-editing proteins. Biomaterials. 2018. |
76-O17Se is a selenium-containing lipidoid investigated for intracellular delivery of mRNA and genome-editing proteins. In CAR-T cell engineering studies, 76-O17Se-based lipid nanoparticles delivered N1-methylpseudouridine-modified anti-CD19 CAR mRNA into CD8+ T lymphocytes. The resulting CAR-T cells demonstrated cytotoxic activity against B-cell lymphoma cells in vitro, supporting its application in nonviral mRNA delivery and transient immune-cell engineering research.
Specifications shown are product-page values, not batch test results.
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