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NT1-O14B

Version 1.98c58b69 · 2026-09-13

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CAS No.Not available
Chemical NameNT1-O14B
SynonymsNT1O14B， NT1 O14B
SMILESO=C(OCCSSCCCCCCCCCC)CCN(CCC1=CNC2=C1C=CC=C2)CCC(OCCSSCCCCCCCCCC)=O
FormulaC40H68N2O4S4
M.Wt769.230
PurityELSD-HPLC>95%
StorageOriginal product: up to 1 year under the storage conditions stated on the vial, kept tightly sealed. Stock solutions: aliquots at -20°C, generally up to one month.
Shipping conditionShips from Shanghai. Pure lipid is stable during ice-pack transport.
Publication1. Ma, F., Yang, L., Sun, Z., et al. Neurotransmitter-derived lipidoids (NT-lipidoids) for enhanced brain delivery through intravenous injection. Sci. Adv. 6(30), eabb4429 (2020).

NT1-O14B is a tryptamine-containing cationic lipidoid.1 It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs). Intravenous administration of LNPs containing NT1-O14B and encapsulating antisense nucleotides against tau decreases tau brain levels in mice.

Specifications shown are product-page values, not batch test results.

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