DC Chemicals

DC57046 · Updated 27 October 2026

ATX-126 (ATX-0126, lipid 10p)

Product Datasheet

ATX-126 is a thiocarbamate-containing ionizable lipid investigated in siRNA nanoparticles and identified as an LNP component in the PMDA assessment of Kostaive.

CAS No.2230647-37-5
Chemical NameATX-126(ATX-0126, lipid 10p)
SynonymsATX126, ATX 126,ATX 0126, ATX0126,ATX100,ATX-100, ATX 100
SMILESCCCCCCCC(CCCCCCC)OC(=O)CCCN(CCCC(=O)OC(CCCCCCC)CCCCCCC)C(=O)SCCCN(C)C
FormulaC44H86N2O5S
M.Wt755.23
Purity>95% by ELSD-HPLC
StoragePure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light.
Shipping conditionShips from Shanghai. Pure lipid is stable during ice-pack transport.
Publication
  1. Rajappan K, et al. Property-Driven Design and Development of Lipids for Efficient Delivery of siRNA. J Med Chem 63 (2020), 12992–13012.
  2. PMDA. Kostaive Intramuscular Injection review report. Sections 2.2.1, 4.2.2 and 4.3.

Research evidence

Read detailed Formulation & Performance

Specifications are catalog specifications, not batch test results.