All products / DC29000
(R)-CR8 trihydrochloride
Pack sizes and prices
| Pack size | Price |
|---|---|
| 100mg | $350 USDRequest a quote / confirm availability → |
| 250mg | $550 USDRequest a quote / confirm availability → |
| 1g | $1,200 USDRequest a quote / confirm availability → |
Confirm stock, lead time, shipping and final quotation with our team.
Product overview
(R)-CR8 trihydrochloride (CR8 trihydrochloride), a second-generation derivative of Roscovitine, is a highly potent inhibitor of CDK1/2/5/7/9. It exhibits inhibitory activity against CDK1/cyclin B (IC50=0.09 μM), CDK2/cyclin A (0.072 μM), CDK2/cyclin E (0.041 μM), CDK5/p25 (0.11 μM), CDK7/cyclin H (1.1 μM), CDK9/cyclin T (0.18 μM), and CK1δ/ε (0.4 μM). (R)-CR8 trihydrochloride induces apoptosis and demonstrates neuroprotective properties.
For research use only. Results depend on experimental conditions and do not constitute a performance guarantee.
Identity and specifications
| Catalog number | DC29000 |
|---|---|
| Product name | (R)-CR8 trihydrochloride |
| CAS | 1786438-30-9 |
| Molecular formula | C24H32Cl3N7O |
| Molecular weight | 540.9162 |
| Purity | 98% |
| SMILES | CC[C@H](CO)Nc1nc(NCc2ccc(-c3ccccn3)cc2)c2ncn(C(C)C)c2n1.Cl.Cl.Cl |
Source-listed specifications; the batch COA applies.
Source and product documents
The supplier source is linked below. Contact us for COA, SDS and batch-specific documents.
DC Chemicals — (R)-CR8 trihydrochloride (DC29000)