Literature-reported formulation composition
Component: EA-PIP (Lipid 10) | mol%: 50 | Role: Ionizable lipid
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EA-PIP (Lipid 10)
Literature records
Search the tables and observations reproduced from the product literature guide. Rows may represent measurements, recipes or experimental context; they are not all independent experiments.
Literature-reported formulation composition
Component: Cholesterol | mol%: 38.5 | Role: Sterol
Literature-reported formulation composition
Component: DSPC | mol%: 10 | Role: Helper phospholipid
Literature-reported formulation composition
Component: DMG-PEG2000 | mol%: 1.5 | Role: PEG lipid
Literature-reported formulation composition
Component: Reported total | mol%: 100 | Role: Source values retained
Reported observation
Literature-reported CAG viability after CKAP5-siRNA treatment 4.17% Unmodified L10 LNP; 0.1 microgram/mL total RNA; XTT, normalized to negative-control siRNA · 72 h Main PDF p.2 and Fig.1G
Reported observation
Literature-reported CKAP5 mRNA reduction 73.5% CAG cells; 0.1 microgram/mL siRNA · 24 h Main PDF p.2 and Fig.2A
Reported observation
Targeted formulation is separate Lipid10/cholesterol/DSPC/PEG-DMG/DSPE-PEG-maleimide = 50:38:10:1.9:0.1 molar, followed by anti-CD38 THB-7 conjugation. This is required context for the bone-marrow multiple-myeloma experiments. Do not attribute antibody-mediated targeting to naked Lipid10. · Main PDF pp.10-11, Methods