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PRODUCT USE GUIDE · DC86070

304O13

Instructions for Use

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Product information

304O13 is a novel Biodegradable lipidoid for RNA delivery.

CAS No.Not available
Chemical Name304O13
FormulaC57H116N4O6
M.Wt951.54
Purity>95%
StorageOriginal product: up to 1 year under the storage conditions stated on the vial, kept tightly sealed. Stock solutions: aliquots at -20°C, generally up to one month.
Shipping conditionShips from Shanghai. Pure lipid is stable during ice-pack transport.

Formulation & study context

Literature information refers to the cited study and its particular formulation. Administration routes are research context, not clinical instructions or a guarantee of performance.

A complete product-specific formulation has not been verified. No standard ratio is substituted.

N/P ratioNot reported in the verified record
CargoNot available in the verified record
Administration routeNot available in the verified record
Animal modelNot available in the verified record
Formulation processNot available in the verified record

N/P is the molar ratio of specified lipid nitrogen groups to nucleic-acid phosphate groups. A lipid:cargo mass ratio is a different quantity and must not be used as N/P.

Stock-solution preparation table

Calculated from the product-page molecular weight: 951.54 g/mol. Volumes are final solution volumes.

Lipid mass1 mM5 mM10 mM
10 mg10.509 mL2.102 mL1.051 mL
25 mg26.273 mL5.255 mL2.627 mL
50 mg52.546 mL10.509 mL5.255 mL
100 mg105.093 mL21.019 mL10.509 mL
250 mg262.732 mL52.546 mL26.273 mL

Volume (mL) = mass (mg) × 1000 / [MW (g/mol) × concentration (mM)]. These are mathematical conversions, not measured solubility or validated solvent recommendations. Confirm solvent compatibility and the molecular weight of the exact material before use.

Open editable solution calculators →

Handling & storage

Provided that storage conditions are as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 1 year.

Wherever possible, prepare and use solutions on the same day. If stock solutions must be prepared in advance, store them as aliquots in tightly sealed vials at -20°C. Generally, these will be usable for up to one month.

Before use, and prior to opening the vial, allow the product to equilibrate to room temperature for at least 1 hour.

References

Whitehead, K. A.; Dorkin, J. R.; Vegas, A. J.; Chang, P. H.; Veiseh, O.; Matthews, J.; Fenton, O. S.; Zhang, Y.; Olejnik, K. T.; Yesilyurt, V.; et al. Degradable Lipid Nanoparticles with Predictable In Vivo siRNA Delivery Activity. Nat. Commun. 2014, 5, 4277.