YK-009
Version 1.bfbd107d · 2026-09-13
| CAS No. | Not available |
| Chemical Name | YK-009 |
| Synonyms | YK009, YK 009 |
| SMILES | CCCCCCCCCCOC(=O)CCCN(CCO)CCCCCC(=O)OCC(CCCCCCCC)CCCCCCCC |
| Formula | C40H79NO5 |
| M.Wt | 654.06 |
| Purity | >95% |
| Storage | Original product: up to 1 year under the storage conditions stated on the vial, kept tightly sealed. Stock solutions: aliquots at -20°C, generally up to one month. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | 1. Long, J., Yu, C., Zhang, H., et al. Novel ionizable lipid nanoparticles for SARS-CoV-2 omicron mRNA delivery. Adv. Healthc. Mater. 12(13), 2202590 (2023). |
YK-009 is an advanced, biodegradable ionizable lipid designed for efficient mRNA delivery. Via intramuscular injection, it demonstrates superior targeting to draining lymph nodes, boosting immune cell transfection for vaccines. When administered intravenously, it distributes to the liver but leverages a highly degradable chemical backbone to ensure rapid clearance post-endosomal escape. This effectively eliminates the risk of long-term tissue accumulation and liver toxicity seen in traditional lipids. Delivering a balance of high transfection efficiency and exceptional biocompatibility, YK-009 is an ideal component for safe and potent lipid nanoparticle (LNP) formulations.
Specifications shown are product-page values, not batch test results.
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