DC Chemicals

DC82209 · Updated 28 October 2026

Lipid 10a-26

Instructions for Use

Before use

Check the supplied lot number, batch COA, approved SDS, quantity and retest date. Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light.

For small quantities of viscous or oily lipid, volumetric transfer can reduce weighing losses. Confirm solvent compatibility and solubility before preparing a stock; calculated volumes do not establish solubility.

Stock-solution planning

Volume (mL) = mass (mg) × 1000 / [molecular weight × concentration (mM)].

Mass10 mM20 mM
10 mg1.2464 mL0.6232 mL
25 mg3.1160 mL1.5580 mL
50 mg6.2320 mL3.1160 mL
100 mg12.4640 mL6.2320 mL

Literature formulation reference

ComponentDC Chemicals productMolecular weightMolar ratioMass at 1 µmol total lipid (mg)
Lipid 26 / Lipid 10a-26DC82209802.31620.497432
DSPC (paragraph 0838)DC57005790.1540.031606
CholesterolDCD-041386.65330.127594
DSPE-PEG2000Not uniquely mappedNot established1Not calculable from disclosed data

Paragraph 0838 reports a DSPC variant; paragraph 0839 separately describes a DOPE variant. Both state 16:1:4:1 by weight and 62:4:33:1 by mole. These are retained as patent-reported ratios, not independently validated equivalents. DSPE-PEG2000 MW is unassigned; fixed weighing conversion remains incomplete.

Read the complete study conditions, biological results, tolerability and figures →

References

  1. Wesselhoeft A, Goodman B et al. Circular RNA compositions and methods. WO2021189059A2 (2021). Paragraphs 0838-0844, 0861-0862; Figures 32, 35 and 45.