PRODUCT DATASHEET · DC82101
AA3-DLin
Version 1.24381b34 · 2026-09-13
| CAS No. | Not available |
| Chemical Name | AA3-DLin |
| Synonyms | piperazine-1,4-diylbis(ethane-2,1-diyl) (9Z,9'Z,12Z,12'Z)-bis(octadeca-9,12-dienoate);AA3DLin， AA3 DLin |
| SMILES | O=C(CCCCCCC/C=C\C/C=C\CCCCC)OCCN1CCN(CCOC(CCCCCCC/C=C\C/C=C\CCCCC)=O)CC1 |
| Formula | C44H78N2O4 |
| M.Wt | 699.1 |
| Purity | ELSD-HPLC>95% |
| Storage | Original product: up to 1 year under the storage conditions stated on the vial, kept tightly sealed. Stock solutions: aliquots at -20°C, generally up to one month. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | 1. Li, Z., Zhang, X.-Q., Ho, W., et al. Enzyme-catalyzed one-step synthesis of ionizable cationic lipids for lipid nanoparticle-based mRNA COVID-19 vaccines. ACS Nano 16(11), 18936–18950 (2022). |
AA3-DLin is an ionizable cationic amino lipid (pKa = 5.8) that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA.LNPs containing AA3-DLin and encapsulating mRNA for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein induce immunogenicity in mice.
Specifications shown are product-page values, not batch test results.
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