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Lipid A3B7C2

Version 1.cb95ac21 · 2026-09-13

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CAS No.Not available
Chemical NameLipid A3B7C2
SynonymsA3B7C2
SMILESn1cn(CCN(CCO)CCO)c(-c2cc(OCCCCC(=O)OCCCCCCCCCCCC)c(OCCCCC(=O)OCCCCCCCCCCCC)cc2)c1-c1ccc2ccccc2c1
FormulaC61H95N3O8
M.Wt998.44
Purity>98%
StorageOriginal product: up to 1 year under the storage conditions stated on the vial, kept tightly sealed. Stock solutions: aliquots at -20°C, generally up to one month.
Shipping conditionShips from Shanghai. Pure lipid is stable during ice-pack transport.
PublicationMulticomponent Synthesis of Imidazole-Based Ionizable Lipids for Highly Efficient and Spleen-Selective Messenger RNA Delivery-Journal American Chemical Society (2024) 146 (22): 15085–15095.

A3B7C2 is an imidazole‑based ionizable lipid, featuring dimethylamino‑imidazole head group connected via ester‑type degradable C2‑linker to two C14 unsaturated aliphatic tails. It forms LNPs achieving 98 % splenic transfection proportion, potent for splenic dendritic cell‑targeted mRNA delivery, superior to MC3, SM102.

Specifications shown are product-page values, not batch test results.

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