DC67605 · Updated 28 October 2026
PyCB lipid
Product Datasheet
PyCB lipid is a zwitterionic component studied in PEG-free, three-component LNPs for splenic mRNA delivery. With ALC-0315 and DSPC, the published ThrCo formulation supported immune-cell expression, antigen-specific T-cell responses and antitumour activity in mouse models.
| CAS No. | Not available |
| Chemical Name | PyCB lipid |
| Synonyms | PyCBlipid, PyCB-lipid |
| SMILES | CCCCCCCCC(CCCCCC)C(=O)OCCCCCCN(CCCCCCOC(=O)C(CCCCCC)CCCCCCCC)CCCCOC(=O)C1=CC=[N+](CC(=O)[O-])C=C1 |
| Formula | C56H100N2O8 |
| M.Wt | 929.42 |
| Purity | >95% by ELSD-HPLC |
| Storage | Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication |
Research evidence
Read detailed Formulation & Performance
Specifications are catalog specifications, not batch test results.