PRODUCT DATASHEET · DC67556
Lipid 2308
Version 1.909e9354 · 2026-09-13
| CAS No. | Not available |
| Chemical Name | Lipid 2308 |
| Synonyms | Sail Lipid-2308, Lipid2308, Lipid 2308 |
| SMILES | CCCCCCCCCCCOC(=O)CCCCCN1C[C@@H](OC(=O)CCN(C)C)CC[C@H]1C(=O)OCCCCCCCC(=O)OC(CCCCCCCC)CCCCCCCC |
| Formula | C53H100O8N2 |
| M.Wt | 893.39 |
| Purity | ELSD-HPLC>95% |
| Storage | Original product: up to 1 year under the storage conditions stated on the vial, kept tightly sealed. Stock solutions: aliquots at -20°C, generally up to one month. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | Not available |
Sail Lipid 2308 is a novel ionizable lipid targeting to spleen developed by Sai Biomedicine.As described on US20250205167A1, Lipid 2308 was designed with a piperidine core (6-membered ring) and asymmetric C17/C11 chains, this lipid achieves unprecedented spleen-specificity. It demonstrates dominant spleen accumulation (Spleen RLU: 7.8E+06, 91.8% of total signal) with a record spleen-to-liver ratio of 112.7 (9× higher than 2231). Despite lower protein expression (hEPO: 11,000 ng/mL), near-zero liver uptake (Liver RLU: 66,000) makes Lipid 2308 unparalleled for vaccine/immunotherapy applications targeting splenic immune cells.
Specifications shown are product-page values, not batch test results.
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