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Lipid CS22021

Version 1.a5e04ae5 · 2026-09-13

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CAS No.Not available
Chemical NameLipid CS22021
SynonymsLipid-CS22021, CS22021
SMILESCCCCCCCCC(CCCCCC)C(=O)OCCCCCCN(CCCN1C=CN=C1)CCOC(=O)O[C@H]1CC[C@@]2(C)C(C=C[C@@H]3[C@@H]2CC[C@@]2(C)[C@H]3CC[C@@H]2[C@H](C)CCCC(C)C)C1
FormulaC58H101O5N3
M.Wt920.46
Purity>98%
StorageOriginal product: up to 1 year under the storage conditions stated on the vial, kept tightly sealed. Stock solutions: aliquots at -20°C, generally up to one month.
Shipping conditionShips from Shanghai. Pure lipid is stable during ice-pack transport.
PublicationWang Z, Yan Z, Yan S, et al. Ionizable Sterol Lipid-Based Three-Component Lipid Nanoparticles for Localized Delivery of mRNA Vaccine with Stronger Cellular Immune Responses. ACS Applied Materials & Interfaces. 2025;17(25):36377-36386.

CS22021 is an ionizable sterol lipid studied in three-component LNPs containing a helper phospholipid and M-DMG-PEG2K, without added free cholesterol. The supporting information reports formulation ratios, N/P and particle properties. The published abstract reports localized expression after intramuscular administration and enhanced CD8+ T-cell responses in a preclinical VZV mRNA vaccine study.

Specifications shown are product-page values, not batch test results.

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