DM3-BTA-14
Version 1.51ca2605 · 2026-09-13
| CAS No. | Not available |
| Chemical Name | DM3-BTA-14 |
| Synonyms | DM3BTA14， DM3 BTA 14 |
| SMILES | CCCCCCCCCCCCCCOC(=O)C1=CC(C(=O)OCCCCCCCCCCCCCC)=CC(C(=O)NCCCNC)=C1 |
| Formula | C41H72O5N2 |
| M.Wt | 672.54 |
| Purity | ELSD-HPLC>95% |
| Storage | Original product: up to 1 year under the storage conditions stated on the vial, kept tightly sealed. Stock solutions: aliquots at -20°C, generally up to one month. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | Not available |
DM3-BTA-14 is a cationic lipid compound engineered for high-efficiency mRNA delivery developed by Hefei AlphaNA Biotechnology. Its structure features a rigid benzene-1,3,5-tricarboxamide core linked to a protonatable dimethylamino headgroup (-N(CH₃)₂) via a propylene spacer (-CH₂CH₂CH₂-) and two saturated C14 alkyl chains. This design enables ≈90% endosomal escape efficiency , superior lymph node targeting for vaccines , and effective tumor-specific mRNA delivery . It outperforms benchmark lipids while maintaining low cytotoxicity, forming stable nanoparticles with cholesterol/DSPC/DSPE-PEG (50:39:10:1 ratio) for therapeutic applications.
Specifications shown are product-page values, not batch test results.
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