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CP-LC-1428

Version 1.1613dd69 · 2026-09-13

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CAS No.Not available
Chemical NameCP-LC-1428
Synonyms6-methylheptyl 7-(2-((3-((2-butyloctyl)oxy)-3-oxopropyl)thio)ethyl)-2-methyl-14-((3-((6-methylheptyl)oxy)-3-oxopropyl)thio)-6,9-dioxo-17-thia-2,5,8-triazaicosan-20-oate,CPLC1428, CP LC 1428
SMILESO=C(NCCN(C)C)C(CCSCCC(OCC(CCCC)CCCCCC)=O)NC(CCCCC(CCSCCC(OCCCCCC(C)C)=O)SCCC(OCCCCCC(C)C)=O)=O
FormulaC53H101N3O8S3
M.Wt1,004.6
Purity>98%
StorageOriginal product: up to 1 year under the storage conditions stated on the vial, kept tightly sealed. Stock solutions: aliquots at -20°C, generally up to one month.
Shipping conditionShips from Shanghai. Pure lipid is stable during ice-pack transport.
PublicationNot available

Derived from the natural amino acid homocysteine, CP-LC-1428 is an ionizable cationic lipid that enables highly efficient in vivo delivery of multiple RNA formats (including mRNA, cRNA and saRNA) with robust protein expression. When formulated into standard LNPs (50:38.5:10:1.5 molar ratio of ionizable lipid:cholesterol:DOPE:PEG-lipid), it demonstrates superior spleen-selective targeting compared to conventional delivery systems following intravenous administration, while maintaining an excellent safety profile.

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