DC67295 · Updated 28 October 2026
MK16
Product Datasheet
MK16 is an ionizable lipid studied in blood-brain-barrier-crossing lipid nanoparticles for mRNA delivery. Published studies report expression in mouse brain cells, ex vivo adult human cortical tissue and an orthotopic glioblastoma model. Performance depends on the full formulation, cargo, dose and model.
| CAS No. | Not available |
| Chemical Name | Lipid MK16 |
| Synonyms | Lipid-MK16, MK 16, MK-16, MK16 BL |
| SMILES | CC(OCCCCCC)OCCCCCCN(CCCCCCOC(C)OCCCCCC)CCCCCCNC(CC[C@H]1CC[C@@](C2=CC(F)=CC=C2F)(S(C3=CC=C(Cl)C=C3)(=O)=O)CC1)=O |
| Formula | C55H91ClF2N2O7S |
| M.Wt | 997.84 |
| Purity | >95% by ELSD-HPLC |
| Storage | Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication |
Research evidence
Read detailed Formulation & Performance
Specifications are catalog specifications, not batch test results.