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4-O10b1

Version 1.1e7b7130 · 2026-09-13

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CAS No.Not available
Chemical Name4-O10b1
Synonymstetra(decan-2-yl) 3,3',3'',3'''-((piperazine-1,4-diylbis(propane-3,1-diyl))bis(azanetriyl))tetrapropionate,4O10b1 , 4 O10b1
SMILESCC(CCCCCCCC)OC(CCN(CCC(OC(C)CCCCCCCC)=O)CCCN1CCN(CCCN(CCC(OC(C)CCCCCCCC)=O)CCC(OC(C)CCCCCCCC)=O)CC1)=O
FormulaC62H120N4O8
M.Wt1,049.66
Purity>98%
StorageOriginal product: up to 1 year under the storage conditions stated on the vial, kept tightly sealed. Stock solutions: aliquots at -20°C, generally up to one month.
Shipping conditionShips from Shanghai. Pure lipid is stable during ice-pack transport.
PublicationNot available

4-O10b1 is an ionizable lipid used to generate lipid nanoparticles (LNPs) for delivering RNA to cells. LNPs comprised of 4-O10b1 and conjugated with the macrophage antibody F4/80 were able to delivery siRNA targeting TAK1 to RAW264.7 cells resulting in suppressed activation of NF-kB. Intranasal administration reduced lung injury in an influenza mouse model.

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