PRODUCT DATASHEET · DC66221
E12CA1A3
Version 1.6d265c4d · 2026-09-13
| CAS No. | Not available |
| Chemical Name | E12CA1A3 |
| Synonyms | 2-hexyl-decanoic acid, 2-[4-(dimethylamino)-1-oxobutoxy]dodecyl ester,E12CA1-A3， E12-CA1-A3， E12-CA1A3 |
| SMILES | CCCCCCC(CCCCCCCC)C(OCC(CCCCCCCCCC)OC(CCCN(C)C)=O)=O |
| Formula | C34H67NO4 |
| M.Wt | 553.9 |
| Purity | >98% |
| Storage | Original product: up to 1 year under the storage conditions stated on the vial, kept tightly sealed. Stock solutions: aliquots at -20°C, generally up to one month. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | Not available |
E12CA1A3 is an ionizable cationic lipid (pKa = 6.4) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo.1 LNPs containing E12CA1A3 and encapsulating an mRNA reporter induce luciferase reporter expression in mouse bone marrow-derived dendritic cells (BMDCs) and mice. LNPs containing E12CA1A3 are cleared more rapidly from the liver than LNPs containing DLin-MC3-DMA (Item No. 34364) in mice.
Specifications shown are product-page values, not batch test results.
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