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PRODUCT DATASHEET · DC65701

L-369

Version 1.796698fa · 2026-09-13

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CAS No.Not available
Chemical NameL-369
SynonymsL369, L 369,Lipid 369, Lipid369
SMILESC(OCCC(CCCCC)CCCCC)(=O)CCCCCCCC(OC(=O)CCCN(C)C)CCCCCCCC(OCCC(CCCCC)CCCCC)=O
FormulaC49H95N06
M.Wt794.28
PurityELSD-HPLC>95%
StorageOriginal product: up to 1 year under the storage conditions stated on the vial, kept tightly sealed. Stock solutions: aliquots at -20°C, generally up to one month.
Shipping conditionShips from Shanghai. Pure lipid is stable during ice-pack transport.
PublicationJadhav, V., Vaishnaw, A., Fitzgerald, K., et al. RNA interference in the era of nucleic acid therapeutics. Nat. Biotechnol. 42(3), 394-405 (2024).

L-369 (Lipid 369,L369) is novel class of ionizable lipid for siRNA delivery with improved in vivo elimination profile with excellent translation across species,including NHP, wide safety margin.

Specifications shown are product-page values, not batch test results.

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