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ALC-0315 analogue-2

Version 1.4fccca1c · 2026-09-13

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CAS No.Not available
Chemical NameALC-0315 analogue-2
SynonymsALC0315 analogue2, ALC 0315 analogue 2
SMILESO=C(C(CCCCCCCC)CCCCCC)OCCCCCCN(CCCCCCOC(C(CCCCCCCC)CCCCCC)=O)CCOCCO
FormulaC48H95NO6
M.Wt782.27
PurityELSD-HPLC>95%
StorageOriginal product: up to 1 year under the storage conditions stated on the vial, kept tightly sealed. Stock solutions: aliquots at -20°C, generally up to one month.
Shipping conditionShips from Shanghai. Pure lipid is stable during ice-pack transport.
Publication[1]. WO2022213895A1

ALC-0315 analogue-2 is an analogue of ALC-0315. ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine.

Specifications shown are product-page values, not batch test results.

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