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PRODUCT DATASHEET · DC60942

113-AA-C8C14

Version 1.1aa33a47 · 2026-09-13

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CAS No.Not assigned
Chemical Name113-AA-C8C14
SynonymsNot reported
SMILESCCCCCCCCCCCCCC(=O)OC(CCCCCC)CSCCC(NC(C)=O)C(=O)NCCN(C)CCNC(=O)C(CCSCC(CCCCCC)OC(=O)CCCCCCCCCCCCC)NC(C)=O
FormulaC 61 H 117 N 5 O 8 S 2
M.Wt1112.768 g/mol
Purity98%
StorageOriginal product: up to 1 year under the storage conditions stated on the vial, kept tightly sealed. Stock solutions: aliquots at -20°C, generally up to one month.
Shipping conditionPure lipid, shipped from Shanghai with ice packs.
PublicationGuo Q, Zhang Y, Yang X, et al. β-Hydroxy Thioether-Derived Ionizable Lipids for Spleen-Tropic mRNA Delivery and In Vivo Chimeric Antigen Receptor T Cell Engineering. ACS Nano . 2026;20:14602–14614. DOI: 10.1021/acsnano.6c00706

113-AA-C8C14 is a β-hydroxy thioether-derived ionizable lipid identified through a two-stage lipid-library screen. In the cited study, its optimized LNP formulation preferentially delivered mRNA to the spleen after intravenous administration and was evaluated for transient in vivo generation of CD19-targeting CAR T cells. All formulation and performance data below are literature-reported and remain specific to the stated cargo, preparation process, dose, animal model and administration route.

Specifications shown are product-page values, not batch test results.

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