PRODUCT DATASHEET · DC60917
BHD-C2C2-PipZ
Version 1.06d02d4e · 2026-09-13
| CAS No. | Not available |
| Chemical Name | BHD-C2C2-PipZ |
| Synonyms | BHD C2C2 PipZ |
| SMILES | CCCCCCCCC(CCCCCCCC)OC(=O)CCN(CCC(=O)OC(CCCCCCCC)CCCCCCCC)CCN1CCN(C)CC1 |
| Formula | C47H93O4N3 |
| M.Wt | 764.28 |
| Purity | ELSD-HPLC>95% |
| Storage | Original product: up to 1 year under the storage conditions stated on the vial, kept tightly sealed. Stock solutions: aliquots at -20°C, generally up to one month. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | https://www.biorxiv.org/content/10.64898/2025.12.19.695515v2.full.pdf |
BHD-C2C2-PipZ, as an efficient ionizable cationic lipid, achieves high encapsulation efficiency and controllable release of mRNA through its unique chemical structure. In PEG-free 3P-LNPs, its electrostatic interaction with tripolyphosphate successfully replaces the steric stabilization effect of traditional PEG, offering a new strategy to circumvent PEG immunogenicity. Its hepatic distribution pattern further indicates that LNP design should take into account the heterogeneity of the organ microenvironment.
Specifications shown are product-page values, not batch test results.
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