DC Chemicals

DC60809 · Updated 28 October 2026

6Ac1-C12

Product Datasheet

6Ac1-C12 is a biodegradable ionizable lipid studied in liver- and lung-directed mRNA-LNPs. Published work distinguishes conventional helper-lipid formulations from simplified lung-directed systems and measures organ accumulation, functional expression and cell-type delivery separately.

CAS No.Not available
Chemical Name6Ac1-C12
Synonyms6Ac1C12，， 6Ac1 C12
SMILESCCCCCCCCCCCCN(C)CCC(=O)OCC(COCC(COC(=O)CCN(C)CCCCCCCCCCCC)(COC(=O)CCN(C)CCCCCCCCCCCC)COC(=O)CCN(C)CCCCCCCCCCCC)(COC(=O)CCN(C)CCCCCCCCCCCC)COC(=O)CCN(C)CCCCCCCCCCCC
FormulaC106H208N6O13
M.Wt1774.86
Purity>95% by ELSD-HPLC
StoragePure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light.
Shipping conditionShips from Shanghai. Pure lipid is stable during ice-pack transport.
Publication
  1. Su K, Shi L, Sheng T et al. Reformulating lipid nanoparticles for organ-targeted mRNA accumulation and translation. Nature Communications 15, 5659 (2024). DOI: 10.1038/s41467-024-50093-7
  2. Author Source Data workbook; particle and biological endpoint data

Research evidence

Read detailed Formulation & Performance

Specifications are catalog specifications, not batch test results.