DC60782 · Updated 28 October 2026
Lipid A4B4-S3
Instructions for Use
Before use
Check the supplied lot number, batch COA, approved SDS, quantity and retest date. Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light.
For small quantities of viscous or oily lipid, volumetric transfer can reduce weighing losses. Confirm solvent compatibility and solubility before preparing a stock; calculated volumes do not establish solubility.
Stock-solution planning
Volume (mL) = mass (mg) × 1000 / [molecular weight × concentration (mM)].
| Mass | 10 mM | 20 mM |
|---|---|---|
| 10 mg | 1.3102 mL | 0.6551 mL |
| 25 mg | 3.2755 mL | 1.6377 mL |
| 50 mg | 6.5510 mL | 3.2755 mL |
| 100 mg | 13.1019 mL | 6.5510 mL |
Literature formulation reference
| Component | DC Chemicals product | Molecular weight | Molar ratio | Mass at 1 µmol total lipid (mg) |
|---|---|---|---|---|
| A4B4-S3 | DC60782 | 763.246 | 50 | 0.381623 |
| DSPC | DC57005 | 790.15 | 10 | 0.079015 |
| Cholesterol | DCD-041 | 386.65 | 38.5 | 0.148860 |
| C14-PEG2000 (source identity unresolved) | Not uniquely mapped | Not established | 1.5 | Not calculable from disclosed data |
Main Methods: A4B4-S3 / DSPC / cholesterol / C14-PEG2000 = 50:10:38.5:1.5 mol%. The source describes a phosphoethanolamine-based C14-PEG identity; a unique commercial mapping was not established. Its MW is therefore blank rather than replaced with DMG-PEG2000 2507. N/P and total lipid:RNA mass ratio are not assigned.
Read the complete study conditions, biological results, tolerability and figures →