PRODUCT DATASHEET · DC60575
U-101
Version 1.7471700e · 2026-09-13
| CAS No. | Not available |
| Chemical Name | U-101 |
| Synonyms | U101, U 101 |
| SMILES | OCCN(CCO)CCCN(CCCCCC(OCC(CCCCCC)CCCCCCCC)=O)CCCCCC(OCC(CCCCCC)CCCCCCCC)=O |
| Formula | C51H102N2O6 |
| M.Wt | 839.4 |
| Purity | >95% |
| Storage | Original product: up to 1 year under the storage conditions stated on the vial, kept tightly sealed. Stock solutions: aliquots at -20°C, generally up to one month. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | Jiang, Y., Zhang, Y., Liu, C., et al. Tumor-activated IL-2 mRNA delivered by lipid nanoparticles for cancer immunotherapy. J. Control. Release 368, 663-675 (2024). |
U-101 is an ionizable lipid for mRNA delivery. U101-LNP/IL-2F mRNA formulation demonstrats effective antitumor activity and safety.LNPs containing lipid U 101 and encapsulating mRNA encoding a fusion protein composed of IL-2, a linker, and CD25 inhibit tumor growth in an MC-38 mouse xenograft model.
Specifications shown are product-page values, not batch test results.
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