DC60564 · Updated 27 October 2026

Lipid GVS-18-B6

Instructions for Use

Before use

Check the supplied lot number, batch COA, approved SDS, quantity and retest date. Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light.

For small quantities of viscous or oily lipid, volumetric transfer can reduce weighing losses. Confirm solvent compatibility and solubility before preparing a stock; calculated volumes do not establish solubility.

Stock-solution planning

Volume (mL) = mass (mg) × 1000 / [molecular weight × concentration (mM)].

Mass	10 mM	20 mM
10 mg	1.6834 mL	0.8417 mL
25 mg	4.2084 mL	2.1042 mL
50 mg	8.4168 mL	4.2084 mL
100 mg	16.8336 mL	8.4168 mL

Literature formulation reference

Component	DC Chemicals product	Molecular weight	Molar ratio	Mass at 1 µmol total lipid (mg)
GVS-18-B6	DC60564	594.05	54.6	Not calculable from disclosed data
DSPC	DC57005	790.15	10.9	Not calculable from disclosed data
Cholesterol	DCD-041	386.65	32.8	Not calculable from disclosed data
mPEG-DMA	Not uniquely mapped	Not established	1.6	Not calculable from disclosed data

The nominal ratio is from Materials and Methods, LNP Production, in the order GVS-18-B6:DSPC:cholesterol:PEG lipid. Its rounded total is 99.9. SI Table S2 identifies mPEG-DMA and separately reports pre- and post-formulation measurements. PEG molecular weight and exact catalog mapping remain unassigned, so a complete mass conversion is not prefilled. The low-PEG hemolysis formulation is a separate experiment. No N/P value is inferred.

Read the complete study conditions, biological results, tolerability and figures →

Lipid GVS-18-B6

Before use

Stock-solution planning

Literature formulation reference

References