DC Chemicals

DC60537 · Updated 28 October 2026

C18 NC-TNP

Product Datasheet

C18 NC-TNP is a noncationic thiourea lipid studied in a two-component mRNA carrier with cholesterol. Published mouse experiments report prolonged expression after subcutaneous injection, lymph-node immune-cell delivery and spleen-associated distribution after intravenous injection.

CAS No.Not available
Chemical NameC18 NC-TNP
SynonymsC18 NC TNP , C18NCTNP
SMILESCCCCCCCCCCCCCCCCCCOC(=O)CCC(C(=O)OCCCCCCCCCCCCCCCCCC)NC(NCC(O)CO)=S
FormulaC45H88O6N2S
M.Wt785.274
Purity>95% by ELSD-HPLC
StoragePure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light.
Shipping conditionShips from Shanghai. Pure lipid is stable during ice-pack transport.
Publication
  1. Wang C, et al. Biomimetic noncationic lipid nanoparticles for mRNA delivery. PNAS 120, e2311276120 (2023). DOI: 10.1073/pnas.2311276120.
  2. Full text and SI Appendix: main Figs. 1–5; supplementary immune-memory experiments.

Research evidence

Read detailed Formulation & Performance

Specifications are catalog specifications, not batch test results.