PRODUCT DATASHEET · DC60510
Iso-A11B5C1
Version 1.ff1e6400 · 2026-09-13
| CAS No. | Not available |
| Chemical Name | Iso-A11B5C1 |
| Synonyms | IsoA11B5C1, Iso A11B5C1, iso-A11B5C1, H3 |
| SMILES | CCCCCCCC/C=C\CCCCCCCCNC(=O)C(CCCCCOC(=O)CCC(C)CCCCC)NCCN1CCCC1 |
| Formula | C41H79N3O3 |
| M.Wt | 662.10 |
| Purity | ELSD-HPLC>95% |
| Storage | Original product: up to 1 year under the storage conditions stated on the vial, kept tightly sealed. Stock solutions: aliquots at -20°C, generally up to one month. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | Chen J, Xu Y, Zhou M, et al. Combinatorial design of ionizable lipid nanoparticles for muscle-selective mRNA delivery with minimized off-target effects. Proceedings of the National Academy of Sciences of the United States of America. 2023;120(50):e2309472120. |
Iso-A11B5C1 is an asymmetric Ugi-reaction-derived ionizable lipid selected for muscle-focused mRNA delivery. In the cited mouse study, its optimized LNP produced muscle expression comparable to an SM-102 benchmark after intramuscular administration while showing no measurable reporter expression in the examined off-target organs. The same formulation delivered Cre mRNA for localized muscle gene editing and was evaluated with model-antigen and cancer-vaccine mRNAs. All formulation and performance information shown below is literature-derived study evidence, not a product specification or a guarantee of reproducible LNP performance.
Specifications shown are product-page values, not batch test results.
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