PRODUCT DATASHEET · DC60503
C12-A1
Version 1.161b3c0a · 2026-09-13
| CAS No. | Not available |
| Chemical Name | C12-A1 |
| Synonyms | C12A1 ， C12 A1 |
| SMILES | C(CCCCCCCCCC)(O)CN(CCCCCN(CCN1CCN(CCCCCN(CC(CCCCCCCCCC)O)CC(CCCCCCCCCC)O)CC1)CC(CCCCCCCCCC)O)CC(CCCCCCCCCC)O |
| Formula | C76H157N5O5 |
| M.Wt | 1,220.22 |
| Purity | ELSD-HPLC>95% |
| Storage | Original product: up to 1 year under the storage conditions stated on the vial, kept tightly sealed. Stock solutions: aliquots at -20°C, generally up to one month. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | mRNA Lipid Nanoparticles for Ex Vivo Engineering of Immunosuppressive T Cells for Autoimmunity Therapies Ajay S. Thatte, Alex G. Hamilton, Benjamin E. Nachod, Alvin J. Mukalel, Margaret M. Billingsley, Rohan Palanki, Kelsey L. Swingle, and Michael J. Mitchell*-Nano Letters-2023,Oct-30 |
Lipid C12-A1 is an ionizable lipid. C12-A1-LPN is a potent and safe LNP platform to deliver Foxp3 mRNA to CD4+ T cells to engineer immunosuppressive FP3T cells. C12-A1 has a slightly lower average cell viability than C14-A1.
Specifications shown are product-page values, not batch test results.
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