DC60502 · Updated 28 October 2026
GalNAc Lipid GL6 (GalNAc Lipid 1004)
Product Datasheet
GL6 is a trivalent GalNAc lipid ligand studied as an ASGPR-targeting component of lipid nanoparticles. In mouse and cynomolgus-monkey experiments it enabled hepatic ANGPTL3 base editing despite LDLR deficiency. GL6 is the targeting component of a multi-lipid formulation; the ionizable amino lipid used in the paper was not structurally disclosed.
| CAS No. | Not available |
| Chemical Name | GalNAc Lipid GL6(GalNAc Lipid 1004) |
| Synonyms | GalNAc Lipid-GL6 |
| SMILES | CCCCCCCCCCCCCCCCCCOC[C@H](COC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)NC(CCCCNC(=O)CCCCOC1OC(CO)C(O)C(O)C1NC(C)=O)C(=O)N(CCCNC(=O)CCCCOC1OC(CO)C(O)C(O)C1NC(C)=O)CCCNC(=O)CCCCOC1OC(CO)C(O)C(O)C1NC(C)=O)OCCCCCCCCCCCCCCCCCC |
| Formula | C166H319O63N9 |
| M.Wt | 3,449.38 |
| Purity | >95% by ELSD-HPLC |
| Storage | Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication |
Research evidence
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Specifications are catalog specifications, not batch test results.