DC Chemicals

DC60478 · Updated 27 October 2026

ALC-0366

Product Datasheet

ALC-0366 is the ionizable lipid explicitly listed in the BNT142 RNA-LNP formulation disclosed in US20250009780A1. The patent reports formulation composition, in vivo production of a CLDN6×CD3-binding antibody and bounded preclinical tolerability data.

CAS No.Not available
Chemical NameALC-0366
SynonymsALC0366, ALC 0366,ALC366, ALC 366, ALC-366
SMILESOCCCN(CCCCCCCCCOC(C(CCCC)CCCCCC)=O)CCCCCCCCCOC(C(CCCC)CCCCCC)=O
FormulaC45H89NO5
M.Wt724.2
Purity>95% by ELSD-HPLC
StoragePure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light.
Shipping conditionShips from Shanghai. Pure lipid is stable during ice-pack transport.
Publication
  1. BioNTech SE. US20250009780A1: Agents encoding CLDN6 and CD3 binding elements for treating CLDN6-positive cancers. Published January 9, 2025. Examples 1–2; Tables 2 and 4; Figures 11–12.

Research evidence

Read detailed Formulation & Performance

Specifications are catalog specifications, not batch test results.