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Lipid Catechol

Version 1.41ca5937 · 2026-09-13

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CAS No.Not available
Chemical NameLipid Catechol
SynonymsLipid-Catechol
SMILESOC1=CC=C(C(P(OCCCCCCCCCCCCCC)(OCCCCCCCCCCCCCC)=O)NCCN(CC)CC)C=C1O
FormulaC41H79N2O5P
M.Wt711.1
Purity98%
StorageOriginal product: up to 1 year under the storage conditions stated on the vial, kept tightly sealed. Stock solutions: aliquots at -20°C, generally up to one month.
Shipping conditionShips from Shanghai. Pure lipid is stable during ice-pack transport.
PublicationNot available

Lipid catechol is a lipid that contains an α-aminophosphonate group, two 14-carbon acyl chains, and a catechol ring that forms a covalent bond with boronic acid-containing compounds to form lipid prodrug nanoassemblies (LPNA).1 LPNAs composed of lipid catechol conjugated to phenylboronic acid-modified ciprofloxacin (CIP-PBA) inhibit the formation of, and disrupt preformed, S. aureus biofilms and eradicate staphylococci in a mouse model of peritoneal S. aureus infection. LPNAs composed of lipid catechol conjugated to bortezomib (BTZ) reduce tumor growth and increase survival in a 4T1 murine mammary carcinoma model.

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