PRODUCT DATASHEET · DC49883
L343
Version 1.259cec41 · 2026-09-13
| CAS No. | Not available |
| Chemical Name | L343 |
| Synonyms | L 343， L-343，lipid 343 |
| SMILES | O=C(OC(C)(C)C)CCCCCCC/C=C\CCCCCCCCC(OC(CCCN(C)C)=O)CCCCCCCC/C=C\CCCCCCCC(OC(C)(C)C)=O |
| Formula | C51H95NO6 |
| M.Wt | 818.30 |
| Purity | >98% |
| Storage | Original product: up to 1 year under the storage conditions stated on the vial, kept tightly sealed. Stock solutions: aliquots at -20°C, generally up to one month. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | [1]. Maier MA, Jayaraman M, Matsuda S, et al. Biodegradable lipids enabling rapidly eliminated lipid nanoparticles for systemic delivery of RNAi therapeutics. Mol Ther. 2013;21(8):1570-1578. |
L-343 is an ionizable cationic lipidoid and can be used to synthetic liposomes for systemic delivery of RNAi therapeutics, Pka: 6.34.L343, with its sterically hindered tert-butyl esters, exhibited slower elimination from plasma and higher and more persistent levels in liver compared with L319.
Specifications shown are product-page values, not batch test results.
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