All products / DC77410
BMS-986449
Pack sizes and prices
| Pack size | Price |
|---|---|
| 100 mg | $1,800 USDRequest a quote / confirm availability → |
Confirm stock, lead time, shipping and final quotation with our team.
Product overview
BMS-986449 is a CELMoD molecular glue and an IKZF2/IKZF4 degrader. BMS-986449 targets the degradation of transcription factors Helios (IKZF2) and Eos (IKZF4) in regulatory T (Treg) cells. BMS-986449 redirects the E3 ubiquitin ligase Cereblon to induce the degradation of Helios and Eos, reprogramming Treg cells and enhancing antitumor immunity. BMS-986449 is promising for research of advanced solid tumors.
For research use only. Results depend on experimental conditions and do not constitute a performance guarantee.
Identity and specifications
| Catalog number | DC77410 |
|---|---|
| Product name | BMS-986449 |
| Molecular formula | C21H21FN4O3 |
| Molecular weight | 396.41 |
| SMILES | Cc1cc(-c2ccc3c(c2F)[C@@H](C)N([C@H]2CCC(=O)NC2=O)C3=O)nc(N)c1C |
Source-listed specifications; the batch COA applies.
Source and product documents
The supplier source is linked below. Contact us for COA, SDS and batch-specific documents.
DC Chemicals — BMS-986449 (DC77410)