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HQ005
CAT. NO. DC72726

HQ005

Pack sizes and prices

Pack sizePrice
100 mg$1,350 USDRequest a quote / confirm availability →

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Product overview

HQ005 is a highly efficient molecular glue degrader that induces the selective degradation of ​Cyclin K (CCNK) with exceptional potency (DC50 = 41 nM). By facilitating novel protein-protein interactions between ​CCNK and the ​ubiquitin-proteasome system, HQ005 promotes targeted ubiquitination and proteasomal clearance of CCNK, offering a precise pharmacological tool for modulating ​CDK12/13-dependent transcription and ​DNA damage response pathways.

For research use only. Results depend on experimental conditions and do not constitute a performance guarantee.

Identity and specifications

Catalog numberDC72726
Product nameHQ005
CAS2750644-31-4
Molecular formulaC15H15N5O2S2
Molecular weight361.44
Purity>98%
SMILESCc1cnc(NC(=O)Cc2csc(Nc3cccc(CO)n3)n2)s1

Source-listed specifications; the batch COA applies.

Source and product documents

The supplier source is linked below. Contact us for COA, SDS and batch-specific documents.

DC Chemicals — HQ005 (DC72726)

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