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tri-GalNAc-PEG3-Azide
CAT. NO. DC68015

tri-GalNAc-PEG3-Azide

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Pack sizePrice
25mg$1,100 USDRequest a quote / confirm availability →

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Product overview

tri-GalNAc-PEG3-Azide is a functionalized asialoglycoprotein receptor (ASGPR) ligand for lysosomal targeting chimera (LYTAC) research and development; each molecule incorporates three ASGPR ligands with a PEG3 linker and azide group reactive handle ready for conjugation. Upon binding to the ASGPR, tri-GalNAc conjugates are efficiently internalized via ASGPR-mediated endocytosis. tri-GalNAc conjugation can be employed as a strategy to effectively deliver cargo such as RNA or Cas9 complexes in a cell-specific manner to hepatocytes. Can be used to generate LYTACs, or labeled with dye for tissue imaging.

For research use only. Results depend on experimental conditions and do not constitute a performance guarantee.

Identity and specifications

Catalog numberDC68015
Product nametri-GalNAc-PEG3-Azide
CAS2925590-71-0
Molecular formulaC70H125N13O31
Molecular weight1644.83
Purity>98%
SMILESCC(=O)N[C@@H]1[C@H](OCCCCC(=O)NCCCNC(=O)CCOCC(COCCC(=O)NCCCNC(=O)CCCCO[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2NC(C)=O)(COCCC(=O)NCCCNC(=O)CCCCO[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2NC(C)=O)NC(=O)CCOCCOCCOCCN=[N+]=[N-])O[C@H](CO)[C@H](O)[C@@H]1O

Source-listed specifications; the batch COA applies.

Source and product documents

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DC Chemicals — tri-GalNAc-PEG3-Azide (DC68015)

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