All products / DC67462
CAT. NO. DC67462
YJ1206
Pack sizes and prices
| Pack size | Price |
|---|---|
| 25mg | $600 USDRequest a quote / confirm availability → |
Confirm stock, lead time, shipping and final quotation with our team.
Product overview
YJ1206 is an orally bioavailable PROTAC compound that selectively degrades CDK12 and CDK13, demonstrating potent activity (IC50 = 12.55 nM) in VCaP cells. It induces DNA damage, triggers apoptosis, and drives tumor regression in treatment-resistant prostate cancer PDX models, highlighting its therapeutic potential.
For research use only. Results depend on experimental conditions and do not constitute a performance guarantee.
Identity and specifications
| Catalog number | DC67462 |
|---|---|
| Product name | YJ1206 |
| CAS | 3053716-98-3 |
| Molecular formula | C49H52FN11O5 |
| Molecular weight | 894.01 |
| Purity | >98% |
| SMILES | O=C1CCC(N2C(=O)c3cc(F)c(N4CCC(N5CCN(c6ccc(N(C(=O)NCc7ccccc7)[C@H]7CC[C@H](Nc8ncc9ccccc9n8)CC7)cn6)CC5)CC4)cc3C2=O)C(=O)N1 |
Source-listed specifications; the batch COA applies.
Source and product documents
The supplier source is linked below. Contact us for COA, SDS and batch-specific documents.
DC Chemicals — YJ1206 (DC67462)