All products / DC60948
NEK7 degrader (Compound 17)
Pack sizes and prices
| Pack size | Price |
|---|---|
| 10mg | $1,200 USDRequest a quote / confirm availability → |
Confirm stock, lead time, shipping and final quotation with our team.
Product overview
NEK7 degrader-1 is a NEK7 molecular glue degrader with a DC50 of 9 nM. NEK7 degrader-1 dose-dependently inhibits caspase-1 activity and IL-Ιβ release in macrophages in response to NLRP3 inflammasome activation. NEK7 degrader-1 can be used for autoinflammatory and autoimmune disorders like multiple sclerosis, neurodegeneraive diseases like Alzheimer's disease and cardiovascular and melabolic disorders like pericarditis and Type 2 diabetes research.
For research use only. Results depend on experimental conditions and do not constitute a performance guarantee.
Identity and specifications
| Catalog number | DC60948 |
|---|---|
| Product name | NEK7 degrader (Compound 17) |
| CAS | 3069891-91-1 |
| Molecular formula | C21H22Cl2N4O3 |
| Molecular weight | 449.330382823944 |
| Purity | 98% |
| SMILES | Cc1cnc(C(C)(C)C(=O)NCc2cc(Cl)c(C3CCC(=O)NC3=O)c(Cl)c2)nc1 |
Source-listed specifications; the batch COA applies.
Source and product documents
The supplier source is linked below. Contact us for COA, SDS and batch-specific documents.
DC Chemicals — NEK7 degrader (Compound 17) (DC60948)