All products / DC45754
CAT. NO. DC45754
ACBI1
Pack sizes and prices
| Pack size | Price |
|---|---|
| 100 mg | $1,200 USDRequest a quote / confirm availability → |
| 250 mg | $1,950 USDRequest a quote / confirm availability → |
| 1 g | $3,900 USDRequest a quote / confirm availability → |
Confirm stock, lead time, shipping and final quotation with our team.
Product overview
ACBI1 is a potent and cooperative PROTAC degrader of SMARCA2, SMARCA4 and PBRM1 with DC50 of 6 nM, 11 nM and 32 nM for SMARCA2, SMARCA4 and PBRM1 in MV-4-11 cells, respectively. ACBI1 is composed of a bromodomain ligand, a linker, and the E3 ubiquitin ligase VHL. ACBI1 induces anti-proliferative effects and apoptosis.
For research use only. Results depend on experimental conditions and do not constitute a performance guarantee.
Identity and specifications
| Catalog number | DC45754 |
|---|---|
| Product name | ACBI1 |
| CAS | 2375564-55-7 |
| Molecular formula | C49H58FN9O7S |
| Molecular weight | 936.1043 |
| Purity | >98% |
| SMILES | Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2(F)CC2)C(C)(C)C)c(OCCOc2ccc(CN3CCN(c4cc(-c5ccccc5O)nnc4N)CC3)cc2)c1 |
Source-listed specifications; the batch COA applies.
Source and product documents
The supplier source is linked below. Contact us for COA, SDS and batch-specific documents.
DC Chemicals — ACBI1 (DC45754)